Nearly 600 admitted to Sheffield’s hospitals with malnutrition since 2015.
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Data also shows there were 2,483 hospital admissions of children and adults due to malnourishment between January and June this year, according to Freedom of Information responses from nearly 50 hospital trusts in England.
Over the past five years, the Sheffield Teaching Hospitals trust reported 587 overall cases of malnutrition in adults and children, the figures show.
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Liberal Democrat leadership hopeful Layla Moran, who collected the data, said she was "shocked" at the figures.
The figures also revealed 915 cases of malnutrition in adults and children have been logged at the Cambridge University Hospitals trust.
The Liverpool Women's Hospital trust reported a case of malnutrition in pregnancy, while the Royal London Free trust and Newcastle upon Tyne Hospitals trust both recorded 656 overall cases in 2020.
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Hide AdSome 80 NHS trusts responded to the Freedom of Information request, while only 50 provided substantive information, according to the MP.
Commenting on the data, Ms Moran said: "Today, in the UK, thousands of friends, relatives, neighbours and colleagues are at risk of the effects of malnutrition.
"These figures shocked me and make me angry that in Britain, in 2020, people can be hospitalised due to malnutrition.
"We need to move forward and create a system of social security that helps everyone and makes sure no one goes hungry in our country.
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Hide Ad"The reasons for fixing this silent crisis are stark. Malnutrition and mortality are usually closely linked.
"Malnutrition lengthens hospital stays, reduces quality of life and increases the risk of developing other diseases."